Publish date:

Hennepin Healthcare to launch clinical trials of coronavirus antiviral

HCMC will be the site of a global clinical trial.

Hennepin Healthcare has announced it has launched two clinical trials to study the safety of using an antiviral drug created for Ebola patients on those with the coronavirus.

The Hennepin Healthcare Research Institute (HHRI), the medical research organization based at Hennepin County Medical Center, says it will be trialing the drug Remdesivir on patients with moderate or severe COVID-19.

Remdesivir is an antiviral developed by Gilead Sciences and was previously tested on patients with Ebola, and has shown "antiviral activity" against other coronavirus-caused contagions such as MERS and SARS.

HCMC will become a clinical site for what is a broad range of international multi-center randomized trials to treat COVID-19, which will see 70 coronavirus patients enrolled in Minnesota out of 1,000 worldwide.

Sign up for our BREAKING NEWS newsletters

"We are proud to be a site that’s conducting research on this investigational treatment,” said HHRI’s Principal Investigator Jason Baker, MD, MS.

"The clinical trials will help to determine if remdesivir is a safe and effective drug that can improve outcomes for patients diagnosed with COVID-19 here at Hennepin Healthcare and in the broader community.”

Patients who qualify for the trial will have to give their consent to be involved, otherwise a legally authorized representative can give consent on their behalf if they're too sick.

The treatment with remdesivir will be contrasted with patients who received the standard treatment for moderate to severe coronavirus.

Next Up

Lakeville South

May bomb threat at south metro school traced to Lakeville area kid

Months of investigation led to the digital footprint of the juvenile.

WIkimedia Commons - Frey April 20, 2021

Frey backs creation of Dept. of Public Safety, removal of police staffing minimums

He is in favor of removing police staffing minimums from the city charter – which this November's ballot question would also do.

Foreman tl - Flug-Presley tr - Sturm bl - Pettus br - Go Fund Me and Facebook

St. Paul PD takes over quadruple killing probe after it emerged they died in Minnesota

A "thorough investigation" reveled where the four Minnesotans were killed.

superior national forest

Highway 1 reopens as Greenwood Fire is 80% contained

The highway has been closed for about a month.

covid, vaccine

Minnesota's COVID-19 update for Monday, September 20

Data in Monday reports includes the past Friday, not the weekend. Weekend data is released on Tuesdays.


Driver killed in ATV rollover crash north of Alexandria

The crash occurred in Douglas County Sunday evening.


coronavirus, covid-19

Minnesota set to get shipment of coronavirus antiviral remdesivir

There have been positive initial results in clinical trials.

Mayo clinic

Coronavirus: Mayo Clinic set to roll out antibody test next week

But it will be a while before the test is broadly available.

Screen Shot 2020-03-22 at 2.52.09 PM

Of Minnesota's 169 coronavirus patients, 34 are healthcare workers

It comes amid an ongoing shortage of protective equipment.

Screen Shot 2020-04-14 at 7.29.56 AM

Coronavirus: Mayo Clinic, U of M are now offering antibody tests

Gov. Tim Walz says he wants Minnesota to ramp up its testing before it goes back to work.

Screen Shot 2020-03-13 at 2.59.26 PM

Gov't launching coronavirus screening website, drive-thru clinics in parking lots

President Trump, however, said testing everyone is "totally unnecessary."

Hospital bed

Coronavirus: Announcement on elective surgeries coming Tuesday

Gov. Tim Walz says that the state has built up good ICU and ventilator capacity.