Skip to main content

Pfizer/BioNTech's COVID vaccine is effective in 12-15 year olds

The companies are asking for emergency use authorization.

Pfizer says the COVID-19 vaccine it has developed with Germany's BioNTech has shown 100% efficacy in preventing infection in 12-to-15-year-olds.

The vaccine rollout to American adults is now well underway, and vaccine developers have turned their attention to testing its safety and efficacy in children, with vaccinating the country's students seen as a crucial step in overcoming the pandemic.

On Wednesday, Pfizer announced that a trial of its two-dose vaccine among 2,260 children aged 12 to 15 "demonstrated 100% efficacy and robust antibody responses," based on results that are yet to be peer reviewed.

Of those in the trial, 1,131 received the Pfizer/BioNTech vaccine, with 1,129 receiving a placebo. Eighteen of those in the placebo group contracted COVID-19, with zero children in the vaccine group getting the virus.

The children who received the vaccine received two doses three weeks apart.

In a statement, Pfizer CEO Albert Bourla said the company now intends to submit the data to the FDA to amend its existing Emergency Use Authorization "with the hope of starting to vaccinate this age group before the start of the next school year."

Further tests are continuing in even younger children, with the first doses given in these tests last week.

The study will evaluate the "safety, tolerability, and immunogenicity" from the vaccine in three different age groups: 6 months to two years, two years to five years, and five years to 11 years.

A cohort of 5 to 11 year olds were the first to receive the vaccine, with the companies planning to start vaccinating the 2-5 cohort next week.

Sign up: Subscribe to our BREAKING NEWS newsletters

Most Minnesota schools had resumed in-person learning by the beginning of March, but the state has since seen a rise in COVID-19 rates, with health officials saying younger generations have been behind much of this recent spread.

The state has been urging parents and students to get tested for COVID-19 every two weeks amid the increasing incidence of more contagious variants of COVID-19.

“Across the globe, we are longing for a normal life," said Ugur Sahin, CEO of BioNTech. "This is especially true for our children. The initial results we have seen in the adolescent studies suggest that children are particularly well protected by vaccination, which is very encouraging given the trends we have seen in recent weeks regarding the spread of the B.1.1.7 UK variant."

Next Up


1 dead, 2 with life-threatening injuries in Minnesota crash

The crash happened just after 7:30 p.m. Friday.

Image (1)

School bus carrying students plunges into river southwest of Fargo

None of the kids suffered life-threatening injuries, though some were taken to area hospitals.

Richfield High School

Richfield High School cancels weekend events after shooting

Two men were shot outside the school's football stadium

Screen Shot 2022-09-23 at 10.21.38 PM

Sound of shots, mass panic at Richfield football game streamed live on YouTube

Gunfire caused panic at a varsity football game Friday night.

J. Gordon

K-9 search leads to $36K fentanyl seizure during traffic stop

A traffic stop was made after the vehicle was seen speeding through the area.

Screen Shot 2022-09-23 at 5.20.08 PM

Gov. Walz reacts to Tuesday death of Mankato West student

The governor is a former geography teacher at the high school.

court room

Teen pleads guilty to Minneapolis carjacking, admits to others

The man was yanked out of the vehicle by witnesses before fleeing the scene.

Federal court house

Three plead guilty to roles in murder on Red Lake Reservation

The 2019 murder left another person seriously injured.


Sheriff: Heifer shot and butchered on farmer's pasture near Aitkin

Anyone with information regarding the incident is encouraged to call the Clearwater County Sheriff's Office.


Minneapolis murder suspect arrested in Wisconsin

The man has been wanted by police since the shooting happened in April.


flu shot, vaccine

Pfizer seeks permission for emergency use of COVID-19 vaccine

The drug maker says its vaccine is 95% effective and ready to be deployed.

coronavirus, covid-19

Pfizer, BioNTech SE announce their COVID-19 vaccine is 90% effective

The companies are applying for FDA approval later in November.

Wikimedia Commons - COVID vaccine, pfizer, shot - Martin G

Pfizer says COVID-19 vaccine is effective in kids ages 5-11

The company plans to seek U.S. authorization for the age group soon.

Wikimedia Commons - COVID vaccine, pfizer, shot - Martin G

FDA authorizes Pfizer COVID vaccine for young teens

During the clinical trial, none of the participants that received the vaccine were diagnosed with the virus.

flu shot, vaccine

Moderna says its COVID-19 vaccine appears to be 94.5% effective

It can be stored at a much warmer temperature than Pfizer's vaccine too.

covid vaccine card

FDA gives full approval to Pfizer's COVID-19 vaccine

This approval is expected to lead to more vaccine mandates.

covid-19, vaccine

Reports: FDA expected to OK use of Pfizer vaccine on young teens

Pfizer found its vaccine is very effective for people ages 12-15.

vaccine, covid, moderna

Mayo Clinic: Don't jump to conclusions about vaccine effectiveness study

The study found that vaccines are effective at preventing severe disease, but perhaps not as strong at infection prevention.