Northbound I-35W is blocked near New Brighton after a small aircraft landed on the interstate.
There is a large emergency service presence at the scene, near the junction with County Road E2.
David Stratioti was on the road when the crash happened and called 911. He shared the above picture showing the plane collided with an SUV.
"We were driving home from RiverWest and noticed a low flying plane – like too low for where we were - about a half mile from 694 going North on 35," he said.
"Then all of a sudden we saw the plane try to land in the median and it swiped an SUV. We pulled over and saw the two people in the plane get out and went over to see if everyone was okay in the SUV."
"The wing cut into the left side of the SUV. The engine was smoking but no fire. There were two people in the plane. We only saw one in the SUV, but we're unsure if anyone else was inside."
It's not believed that anybody is seriously injured.
At 9:45 p.m., the Minnesota Department of Transportation said the freeway is likely to be closed for six hours.
The plane is a fixed-wing, single-engine 1979 Bellanca 17-30A registered to a Craig Gifford of Minneapolis.