Skip to main content

A recently published study of 6.2 million people who received an mRNA COVID vaccine found "no serious health effects linked to" the shots.

The study, published in JAMA Friday, asked the following question: "Are mRNA COVID-19 vaccines associated with increased risk for serious health outcomes during days 1 to 21 after vaccination?" 

Vaccine recipients who were part of eight health plan networks, including HealthPartners, were monitored for "health events" in the 21 days after receiving either the Moderna or Pfizer vaccine, over a period from Dec. 14, 2020, to June 26, 2021.

Researchers, after sorting and analyzing the data, "found that no serious health effects could be linked to the two mRNA vaccines currently being used to protect against COVID-19," Minnesota-based HealthPartners said in a news release.

“Our data validates the safety profile of these mRNA vaccines,” said Elyse Kharbanda, MD, senior investigator with HealthPartners Institute and co-author on the study. “Vaccines are our best hope for returning to more normal lives. They help prevent COVID-19 and we can feel even more confident that they’re safe.”

Researchers specifically watched for 23 potential vaccine side effects, including:

  • Encephalitis/myelitis
  • Seizures
  • Guillain-Barre syndrome
  • Acute myocardial infarction
  • Stroke
  • Pulmonary embolism
  • Bell’s palsy
  • Appendicitis
  • Anaphylaxis
  • Multisystem inflammatory syndrome

Researchers kept an eye out for "safety signals" during their analysis, HealthPartners said — signs of recurring, emerging concerns.

Not one of the 23 health events occurred at a rate that triggered a "safety signal," 

The study authors did highlight a couple of serious incidents, however.

First, heart inflammation (myocarditis or pericarditis, depending on which part of the heart is inflamed). Health officials have previously acknowledged some cases of heart inflammation in the week following an mRNA vaccine, mostly among males under the age of 30. They have called such side effects rare, noting it came out to approximately 12.6 heart inflammation cases per million doses administered. 

Heart inflammation cases in teens following a COVID vaccine have been "mild and self-resolving."

In the study published Friday, researchers noted 34 cases of heart inflammation (85% of them in males) among 12- to 39-year-olds. That showed a "slight risk" of 6.3 additional cases per 1 million doses administered, with about 80% hospitalized for a median of one day. 

But researchers said there is no "significant association" between the mRNA vaccines and either myocarditis or pericarditis

Follow Bring Me The News on Twitter for the latest breaking news

HealthPartners also points to a separate recent study that found heart inflammation events were "far more likely" after getting a COVID-19 infection than getting an mRNA vaccine. 

Researchers also mentioned allergic reactions (anaphylaxis) happening more often after the mRNA COVID vaccines than the 1-2 cases per million doses seen with some other vaccines including influenza. Nearly all anaphylaxis incidents after the COVID vaccines occurred among female recipients.

As of Sept. 1, 3,327,769 people in Minnesota have received at least one dose of a COVID vaccine. That includes the Johnson & Johnson vaccine, which was not part of this recently published study.

Next Up

Screen Shot 2022-05-21 at 9.56.21 AM

North High principal Mauri Friestleben returning to finish year

The principal said Friday she had been fired from her role over her support of a student protest.

ambulance

One dead, two injured in wrong-way crash on Hwy. 169

The crash occurred on Highway 169 early Sunday morning.

minneapolis police

Man fatally shot overnight in north Minneapolis

The shooting was reported around 2:20 a.m.

Screen Shot 2022-05-22 at 8.30.08 AM

Campsites closed at Voyageurs National Park due to 'historic' water levels

All backcountry trails and campsites are closed, as well as many frontcountry sites.

state capitol Minnesota

Lawmakers reach agreement on tax cuts ahead of session's end

Lawmakers announced they had reached a deal on a tax bill Saturday ahead of the looming session deadline.

281699116_10226502238438986_800951410789352812_n

Victims of daytime drive-by shooting in Robbinsdale identified

The two men died after a hail of bullets struck a vehicle.

Screen Shot 2022-05-22 at 8.14.37 AM

Source of 'loud explosion' in Brooklyn Park a mystery

The noise was investigated by police, but no source could be determined.

covid, vaccine, booster shots

COVID: All Americans over 50 advised to get a second booster

Cases, hospitalizations and deaths are on the rise again as new COVID variants emerge.

J.W. Peck (left) and Eric Galler.

2 Minnesotans inducted into White Castle's Hall of Fame

White Castle — it's what a man in Minneapolis and another in Woodbury, crave.

Screen Shot 2022-05-21 at 5.46.37 PM

Video shows officers ended pursuit before fatal crash in Anoka

The crash occurred when the driver fled police during an attempted traffic stop in Coon Rapids.

Eli Hart

6-year-old Eli Hart identified as boy found dead in car trunk

The kindergartner's father was trying to get full custody of his son.

IMG_3509

Boy found dead in trunk of car in Mound was kindergartner

"It is horrifying and difficult to process a tragedy of this magnitude, especially in our close-knit community," the superintendent wrote.

Related

pregnant pregnancy pexels

Data shows no increased risk of miscarriage with mRNA vaccines

The research, led by Minnesota-based HealthPartners Institute, was published Thursday.

cdc - flue vaccine shot 2017

COVID vaccines are more protective than natural immunity, study finds

Unvaccinated individuals that had previously been infected were more likely to test positive.

Pixabay - IV fluid drip

Mayo study: Lab-made antibodies may prevent some COVID hospitalizations

The findings only apply to "high-risk" patients with a mild or moderate case of COVID.

vaccine, covid, moderna

Mayo Clinic: Don't jump to conclusions about vaccine effectiveness study

The study found that vaccines are effective at preventing severe disease, but perhaps not as strong at infection prevention.

Flickr - child teenager school mask covid - Jill Carlson

Where are child COVID vaccination rates highest and lowest in Minnesota?

In many counties, fewer than half of all eligible children have received even one dose.

Flickr - moderna covid vaccine vial

Entire Twin Cities metro now above 70% vaccination rate in 16+

The lone holdout, Anoka County, recently passed the 70% threshold.

vaccine, covid

COVID vaccine to be offered at 14 Twin Cities YMCAs

The vaccine will be available to everyone age 12 and up during free clinic events.