A crucial challenge from Rocco Baldelli helped the Twins rally to beat the Indians in Cleveland.
An overturned call in the top of the 7th inning proved to be the catalyst for a vital comeback victory over the in-form Indians in Cleveland.
A Nelson Cruz bomb had given the Twins a 1-0 lead in the 1st, only for Kyle Gibson to surrender a homer to Carlos Santana in the bottom of the third.
An error from Ehire Adrianza allowed Cleveland to then get batters on 1st and 3rd, with Roberto Perez then hitting a base-clearing double to put the home team 3-1 ahead.
Gibson was pulled after just 3.2 innings despite having given up just 1 earned run, with Trevor May brought in to finish his inning.
The Twins left runners in scoring position in both the 5th and the 6th and for a moment it looked like they'd be their own worst enemy, before crucial moment arrived in the 7th.
With men on 1st and 3rd and 2 outs, Max Kepler hit a groundball that would have scored Sano, but Kepler was given out at first. A challenge from Baldelli and the call was overturned, with Kepler safe and Sano scoring.
With the score at 3-2, Jorge Polanco then hammered a double to deep center to score Adrianza and Kepler to give the Twins the lead, which Mitch Garver then extended in the 8th with a solo homer.
Taylor Rogers then became the first Twins pitcher since Rick Aguilera in 1990 to record back-to-back six out saves to secure the first victory of the series and put Minnesota 6.5 games ahead of their divisional rivals.