Adrian Peterson suffered a right-knee injury in the third quarter against the Packers and was quickly ruled out for the rest of the game.
The former NFL MVP had to be assisted off the field and he couldn't put any weight on his right leg. After being examined on the trainer's table, Peterson was helped back to the locker room, still unable to put any weight on the leg.
Peterson is scheduled to undergo an MRI on Monday.
NBC's Michele Tafoya reported that Peterson was in a lot of pain and team trainers were looking at his knee.
With Peterson injured Jerick McKinnon took over as the primary running back.
The Vikings beat the Packers 17-14.