The Timberwolves fell to the New Orleans Pelicans 100-88 Monday night at Target Center.
Anthony Davis had a big night for New Orleans, scoring 24 points and grabbing 11 rebounds for the double-double, while Tyreke Evans and Eric Gordon each chipped in 22.
New Orleans built a 15-point lead in the first half, and the Wolves couldn't dig their way out of the hole.
Injuries to other players forced Wiggins to play more minutes than he had been in the last few games, as teammate Chase Budinger, who had been playing well, left the game with a sprained ankle.
Budinger finished with 18 points, including 9-of-10 from the free throw line.
The Wolves (16-65) close the season on Wednesday against Oklahoma City.