The Timberwolves weren't able to repeat Friday night's winning performance, losing to Memphis Saturday at Target Center, 99-86.
Ricky Rubio just missed his second career triple-double with 23 points, 10 rebounds and nine assists. Derrick Williams scored 19 points.
The Timberwolves had seven of their 17 turnovers in the third quarter.
The Grizzlies' Darrell Arthur scored nine points during a 16-2 run to start the fourth quarter, including a 3-pointer and follow shot, to give the Grizzlies an 81-69 lead with 7 minutes to play, the Associated Press reports. A long jumper and a 3-pointer by Quincey Pondexter stretched the lead to 86-73.
Minnesota was without Nikola Pekovic, who sprained his left ankle in Friday night's victory over Oklahoma City. It's unclear how long he'll be out.