The Twins scored two runs on four hits in the bottom of the seventh inning, and turned a 2-1 deficit into a 3-2 lead off Tigers starter Anibal Sanchez (1-3).
Pelfrey (2-0) held the Tigers to two runs on three hits, while striking out seven in seven innings. Pelfrey, who had to wait 610 days – nearly two years – for his last Major League victory, only had to wait six days this time around.
Danny Santana had his second consecutive three-hit night, finishing 3-for-4 with an RBI. Kurt Suzuki was 2-for-2 with an RBI and Oswaldo Arcia returned to the Twins lineup, going 2-for-3 with a run scored
But Arcia made a big blunder on the bases that could have cost the Twins a few runs.
Phil Hughes (0-4) heads to the mound for the Twins on Wednesday afternoon to face Tigers starter Shane Greene (3-1).