The Twins have been in Minnesota for 56 years, but this is the first time they've lost this many games.
Friday's 7-3 loss to the Chicago White Sox was loss No. 103 on the season for the Twins, breaking the previous record of 102 set by the team back in 1982.
"You kind of get what you deserve," Twins manager Paul Molitor said after the game, via ESPN.
And it was ugly from the first pitch. White Sox 23-year-old lefty Carlos Rodon tied an American League record by striking out seven straight batters to start the game.
Twins starter Tyler Duffey gave up five early runs and was pulled before the third inning was over. His low moment came when rookie Tim Anderson admired a long home run against him.
Duffey failing to earn a victory means the Twins will not finish the season with a 10-game winner. Duffey won 9 games, Ervin Santana won 7, Kyle Gibson has won 6 and no other starter has won more than 4 games.
Technically, since the franchise goes back to the Washington Senators in 1901, this is the fourth-worst season in franchise history. Three Senators teams lost 104, 110 and 113 games in respective seasons.
The Twins wrap up the season with games Saturday and Sunday in Chicago.