It took 16 innings, but the Twins finished off a night to remember in San Juan, Puerto Rico on a walk-off single by Ryan LaMarre to beat the Cleveland Indians 2-1.
The 5-hour, 13-minute game wrapped up after midnight in Puerto Rico when Eddie Rosario, playing in front of his island nation fans, scored the winning run.
"It was unforgettable," Rosario said, via the Twins, "this was one of the best nights of my life."
Fellow Puerto Rican, Jose Berrios, pitched 7 shutout innings for the Twins, his third start this season in which he's pitched at least 7 shutout innings.
"It was crazy, there were a lot of emotions going through my mind," Berrios said. "After the second inning, I was more concentrated. Tonight was a very important night for me and the island of Puerto Rico."
The high-drama game was scoreless until Edwin Encarnacion blasted a solo home run off the foul pole in the top of the 14th, but Minnesota quickly tied the score with a lead-off home run by Miguel Sano in the bottom of the 14th.
Minnesota is off Thursday before starting a three-game series in Tampa Bay on Friday.
Buxton placed on the disabled list
Twins center fielder Byron Buxton didn't play in either game of the Puerto Rico Series because of migraines.
The Twins placed him on the 10-day disabled list and said there's no reason to be concerned beyond that. He's eligible to return April 25.