It's unclear why Buxton isn't starting.
Byron Buxton smashed two home runs, but the White Sox took three out of four games in the series.
The Twins starter went seven innings in a 6-2 victory.
The returns of Byron Buxton and Michael Pineda helped fuel the victory.
Numerous roster moves for the Twins.
Jorge Polanco and Josh Donaldson both homered in the 6-3 win.
The 60-game season begins Friday night in Chicago.
Buxton was carted off the field during Monday's training camp practice.
The Twins outfielder was injured making a catch in center field.
Buxton has a history of playing at an elite level for 60-game stretches.
With plenty of unique changes, baseball will look much different this year.
The season won't start until at least mid-May, which is good and bad news for the Twins.