The juvenile driver was injured and taken to the hospital.
EEE is a rare virus spread by mosquitos that can infect humans.
The incident happened in rural Mazeppa.
The horse was found frozen and dead from a gunshot wound.
The 47-year-old from South Fargo died at the scene.
A man and a woman have been charged with animal mistreatment.
The Princeton family who owns her is expressing sincere thanks to the rescuers.
The horse was also badly injured and died.
She's begging for help to find out who killed her horse.
The Fillmore County Sheriff's Office is investigating.