Randy Dobnak's six earned runs was part of a long afternoon.
Baltimore had lost 16 straight to the Twins and 14 straight overall.
The Twins have won five of their past six games with Wednesday's win over Baltimore.
Byron Buxton left the game in the ninth inning with an apparent injury.
The Twins outfielder is day-to-day with a non-COVID related illness.
The Twins can win the AL Central with a win on Sunday.
Sano smashed a home run onto Waveland Avenue to beat the Cubs on Saturday night.
The Twins starter went seven innings in a 6-2 victory.
Pineda returned from suspension with a solid effort earlier this week.
The returns of Byron Buxton and Michael Pineda helped fuel the victory.
So how is Michael Pineda's suspension going to affect the shortened season?
The season won't start until at least mid-May, which is good and bad news for the Twins.
Twins Daily looks at which version of Pineda the Twins will get in 2020.
Twins Daily explains just how valuable Michael Pineda could be in 2020.
He will start the season still serving a suspension.
Minnesota could still sign Gibson and Pineda as free agents.
Garver's 28th homer broke a 2-2 tie in the bottom of the eighth inning.
A late-one from Target Field.