The crash closed I-94 in Wisconsin for three hours.
The Twin Cities man was pronounced dead at the scene, authorities said.
Officers arrived on the scene and found the motorcyclist "gravely injured."
The incident happened on a highway exit ramp in Minnetonka.
He was riding down I-94 when he crashed and died.
The man from Burnsville died Saturday night.
The motorcyclist was identified as a 33-year-old from Maplewood.
The bike collided with a Dodge Ram.
The boy died at the scene, police say.
The driver suffered life-threatening injuries.
The 20-year-old suffered fatal injuries in the Tuesday evening crash.
A 67-year-old Lindstrom man died in the crash.
The crash happened Monday in Crow Wing County.
The pair was ejected after the motorcycle left the roadway.
It happened in Inver Grove Heights on Thursday.
The crash happened at a curve in the road.
The 27-year-old is a resident of River Falls.
The man and woman on the motorcycle died at the scene.
The 42-year-old motorcyclist died at the scene.
He had been traveling westbound on Interstate 694.