Anthony Edwards scored a career-high 28 points, but it wasn't enough to defeat the defending champs.
The Wolves came back from a 23-point deficit but couldn't complete the comeback.
The Timberwolves star returned in an overtime loss to the Spurs.
As the Wizards star sat out, Washington handed the Timberwolves their third straight loss.
Minnesota opens the season at Brooklyn Wednesday night.
Naz Reid is dominating in the Las Vegas Summer League.